Tackling Unwanted Proteolysis in Plant Production Hosts Used for Molecular Farming

Tackling Unwanted Proteolysis in Plant Production Hosts Used for Molecular Farming

Although the field of molecular farming has significantly matured over the last years, some obstacles still need to be resolved. A major limiting factor for a broader application of plant hosts for the production of valuable recombinant proteins is the low yield of intact recombinant proteins. These low yields are at least in part due to the action of endogenous plant proteases on the foreign r...

Advances in plant molecular farming.

Plant molecular farming (PMF) is a new branch of plant biotechnology, where plants are engineered to produce recombinant pharmaceutical and industrial proteins in large quantities. As an emerging subdivision of the biopharmaceutical industry, PMF is still trying to gain comparable social acceptance as the already established production systems that produce these high valued proteins in microbia...

Plant Breeding and Molecular Farming

Plant molecular farming: opportunities and challenges.

Production of foreign molecules in transgenic plants is anticipated to be an alternative to already established, microbial or animal expression systems with lower production costs. This article reviews the different technologies and approaches currently used to produce economically interesting molecules in plants or plant cell cultures, to evaluate their technical feasibility and economic impli...

Molecular farming of Plant Derived Edible Vaccines

Plant Derived Edible Vaccines Abstract Vaccines have been one of the most farreaching and important public health initiatives of the 20 century. Edible vaccine, in particular, might overcome some of the difficult of production, distribution and delivery associated with traditional vaccine. Transgenic potatoes expressing LT-B were found to induce both serum and secretory antibodies when fed to m...